Genes that contribute to normal cell reproduction, growth and DNA repair are essential for healthy cell function in all organisms. The dog-1 gene plays a role in maintaining the stability of the genome of Caenorhabditis elegans, a tiny worm frequently studied by researchers because it has many molecular characteristics that are central to human biology. However, little is known about how the dog-1 gene functions to maintain genome stability. Jillian Youds is studying how this gene functions in the cell to gain a better understanding of how it contributes to DNA sequence stability. Given that mutations in the genes required for stability are often underlying causes of disease, this research could provide further understanding of the development of cancer. Completed award term, April 2006 Received 2007 MSFHR Trainee Award
Read Jillian Youds’ 2007 Trainee profile
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Research Area
Biomedical
University/Institution
University of British Columbia (Point Grey)
Faculty/Department
Medicine / Medical Genetics
Supervisor
Dr. Ann Rose, Professor, Medicine / Medical Genetics