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2007 Research Trainee Award

Biomedical

Junior Graduate Studentship

Mechanisms of topical calcipotriol mediated tolerance induction
University of British Columbia
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Determination of cleavage site specificity of matrix metalloproteases by assay of a peptide library generated by enzymatic digest of a complete or partial proteome|,|
University of British Columbia (Point Grey Campus)
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Genetic approaches to characterize mammary stem and progenitor cells|,|
University of British Columbia
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Characterizing the role of granzyme B in atherosclerosis and hair loss in apolipoprotein E knockout mice|,|
University of British Columbia
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The affects of Mgat5 modified glycoproteins and galectin-3 on the expression, phosphorylation and function of connexins|,|
University of British Columbia (Point Grey Campus)
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Evaluating the contribution of bone micro-architecture, density and bone|,|strength to fracture at clinically relevant sites using a novel instrument:|,|An Xtreme CT study|,|
University of British Columbia
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Characterizing the molecular mechanisms of adaptor proteins AP-3 and AP-1B function: An integrated analysis|,|
University of British Columbia
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The role of granzyme B in aortic aneurysms|,|
University of British Columbia
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Discovery of immunogenic Salmonella peptides by immunoproteomics|,|
University of British Columbia (Point Grey Campus)
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Characterization of a new checkpoint in hematopoietic stem cell development|,|
University of British Columbia
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T regulatory cells and T helper 17 cells: Interactions between two distinct T cell subsets important for immune homeostasis|,|
University of British Columbia
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The role of Na+/H+ exchangers (NHEs) in pH regulation and brain function|,|
University of British Columbia (Point Grey Campus)
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Elucidating the signal transduction pathways by which the host defence peptide LL-37 initiates immunomodulatory responses by bronchial epithelial cells|,|
University of British Columbia (Point Grey Campus)
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Heme binding and transport by the Staphylococcus aureus Isd system|,|
University of British Columbia (Point Grey Campus)
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The role of RyR2 in palmitate-induced beta-cell apoptosis in primary human and mouse pancreatic islets|,|
University of British Columbia (Point Grey Campus)
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Identification of positive transcriptional regulators of the tap-1 gene|,|
University of British Columbia
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Dissection of Prp24 functional domains using molecular beacons|,|
University of Northern British Columbia
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Functional analysis of cilia's role in obesity|,|
Simon Fraser University
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Leptin regulation of hepatic glucose and lipid metabolism|,|
University of British Columbia (Point Grey Campus)
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Autonomic dysreflexia and axonal plasticity in sympathetic ganglia following spinal cord injury|,|
University of British Columbia
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An investigation of the basis of aminoglycoside resistance in the Burkholderia cepacia complex|,|
University of British Columbia
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Involvement of ErbB4 in excitatory and inhibitory synapse maturation|,|
University of British Columbia
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The role of toll-like receptors in autoimmunity in non-obese diabetic mice|,|
University of British Columbia
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The role of the Rap1 GTPase in mediating the inflammatory and anti-microbial functions of macrophages|,|
University of British Columbia (Point Grey Campus)
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Study of intercellular barrier alterations in enterocytes during Campylobacter jejuni pathogenesis|,|
University of British Columbia (Point Grey Campus)
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Characterization of a kinase implicated in kinetochore function during S phase|,|
University of British Columbia (Point Grey Campus)
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The biological role of bone marrow-derived keratinocyte precursor cells in wound healing|,|
University of British Columbia
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Use of a recombinant fusion protein to expand hematopoietic stem cells in vitro and to elucidate mechanisms that determine the expansion and self-renewal potential of mouse fetal liver and adult hematopoietic stem cells|,|
University of British Columbia
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Identification of microRNAs, their targets and roles in human embryonic stem cells|,|
University of British Columbia
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Modulation of Cav3.2 T-type calcium channels through neuronal nitric oxide synthase activity
University of British Columbia (Point Grey Campus)
Jointly funded with BC Epilepsy Society
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Lentiviral-mediated RNA interference of the multifunctional cellular enzyme, glyceraldehyde-3-phosphate dehydrogenase (GAPDH): Impact on the hepatitis C virus life cycle|,|
University of British Columbia (Point Grey Campus)
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Identification of Enterohaemorrhagic Escherichia coli (EHEC) effector protein binding partners in host intestinal epithelial cells|,|
University of British Columbia (Point Grey Campus)
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The role of CD34 in muscle regeneration|,|
University of British Columbia
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Mechanism of histone variant H2A.Z deposition by SWR1-Com|,|
University of British Columbia
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Identifying the pro-survival actions of glucose-dependent insulinotropic polypeptide on the pancreatic beta cell|,|
University of British Columbia (Point Grey Campus)
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The role of ubiquitin/proteasome system in heart failure|,|
University of British Columbia
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Characterization of a dioxygenase and a hydrolase critical to persistence of Mycobacterium tuberculosis in the macrophage|,|
University of British Columbia (Point Grey Campus)
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PTEN regulates alternative splicing|,|
University of British Columbia
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Palmitoylation in the pathogenesis of Huntington disease
University of British Columbia
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Senior Graduate Studentship

Defining the role of FOXP3 in human CD4+ T cells|,|
University of British Columbia
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Mechanisms for selectivity of vascular-disrupting anti-cancer therapies|,|
University of British Columbia
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Identification of predictive drug response signatures and novel resistance genes by whole genome profiling of lung tumors|,|
University of British Columbia
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Modulating proteolysis in Huntington disease: Eluding the toxic fragment|,|
University of British Columbia (Point Grey Campus)
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The role of Notch in endothelial cell survival and apoptosis|,||,|
University of British Columbia
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Discovery of novel biomarkers in lung cancer using an integrative genomics approach|,|
University of British Columbia
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Investigation of the molecular mechanisms of inactivation of the voltage-gated potassium channels Kv1.5 and Kv4.2|,|
University of British Columbia (Point Grey Campus)
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Nuclear import of the parvovirus minute virus of mice|,|
University of British Columbia (Point Grey Campus)
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The regulatory role of matrix metalloproteinase-8 in inflammation and autoimmunity|,|
University of British Columbia (Point Grey Campus)
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Epigenomic variation in normal and cancer cells|,|
University of British Columbia
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In vivo imaging of neuronal growth and connectivity during activity-dependent learning within the developing brain - exploring the link between morphology and function|,|
University of British Columbia
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In vivo evaluation of the potential role of anti-inflammatory factors involved in the survival and mechanism of action of hRPE-cell implants for Parkinson's Disease|,|
University of British Columbia
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Genetic and epigenetic studies of innate immunity related genes in the development of asthma in childhood: The role of airway epithelial cells|,|
University of British Columbia
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The excitatory and inhibitory synaptic balance in neurodevelopmental disorders: The role of neuroligins|,|
University of British Columbia
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Bioinformatics of sequence indels: Novel applications for protein network analysis, drug target identification and drug development|,|
University of British Columbia
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Elucidating the function of Bardet-Biedl Syndrome (BBS) proteins in Intraflagellar Transport (IFT)|,||,|
Simon Fraser University
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Investigation of the mechanisms of hematopoietic cell generation from human embryonic stem cells|,|
University of British Columbia
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The molecular characterization of murine hematopoietic stem cell self-renewal divisions|,|
University of British Columbia
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Characterizing novel transcripts enriched in human embryonic stem cell lines|,|
University of British Columbia
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Characterizing the role of palmitoylation in the trafficking of multispanning membrane proteins to the cell surface
University of British Columbia
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Assessing reward-entrainment as a means to activating and identifying the food-entrainable pacemaker|,|
Simon Fraser University
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Investigating the role of the O-GlcNAc post-translational modification in the development of type II diabetes and Alzheimer's disease|,|
Simon Fraser University
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The characterization of KiSS1 and GPR54 in breast cancer and other hormonally responsive cancers|,|
University of British Columbia
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Targeting lung cancer genomics: A whole genome approach to predicting drug response|,|
University of British Columbia
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Characterization of retrograde transport machinery and its relationship to Amyotrophic Lateral Sclerosis (ALS) using the yeast model system|,|
University of British Columbia
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Development of fluorinated carbohydrates for use as positron emission tomography imaging agents and pharmacological chaperones in the treatment of lysosomal storage diseases|,|
University of British Columbia (Point Grey Campus)
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Regulatory mechanisms of the anti-apoptotic NAIP gene during cellular stress and malignancy|,|
University of British Columbia
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Adaptive resistance to aminoglycosides in Pseudomonas aeruginosa|,|
University of British Columbia (Point Grey Campus)
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The role of the intestinal microbiota in host response to enteric pathogens|,|
University of British Columbia
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The role of O-Glycosylation in a mouse model of Amyotrophic Lateral Sclerosis|,|
Simon Fraser University
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Systems biology analysis of dynamic cellular pathways|,|
University of British Columbia (Point Grey Campus)
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Testosterone-dependent regulation of arachidonic acid metabolism influences the development of hypertension following insulin resistance|,|
University of British Columbia (Point Grey Campus)
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Mechanism of androgen regulated expression of SESN1, a potential tumor suppressor|,||,|
University of British Columbia
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Volume and shape of the caudate nucleus and putamen as biomarkers for Parkinson's Disease progression|,|
Simon Fraser University
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The role of the DOG-1 helicase in repair of DNA interstrand cross-links in the model organism Caenorhabditis elegans|,|
University of British Columbia (Point Grey Campus)
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Signaling pathways underlying spreading depression and ischemic depolarization|,|
University of British Columbia
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Post Doctoral Fellowship

Characterization of Salmonella Type III effector: Host protein interactions and their contribution to immune evasion|,|
University of British Columbia
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Imaging the remodeling of individual synapses and vessels in the living brain after stroke|,|
University of British Columbia (Point Grey Campus)
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The role of integrin-linked kinase in modulation of vascular smooth muscle migration and atherosclerotic intimal thickening in type II diabetes|,||,||,|
University of British Columbia
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Elucidation of the nature and biological importance of a novel calcofluor white-reactive surface polysaccharide of Campylobacter jejuni important in stress responses and in biofilm formation|,|
University of British Columbia (Point Grey Campus)
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Dietary modulation of mitochondrial function in the prevention of diabetic heart disease|,|
University of British Columbia
Jointly funded with Child & Family Research Institute
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Critical protective role of Toll-like receptor 2 in bacterial induced colitis|,|
University of British Columbia
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Evaluation of the tumour microenvironment in HER-2 positive breast cancer with non-invasive imaging and molecular techniques: Implications for rational combination therapies|,|
University of British Columbia
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Functional characterization of the chorea-acanthocytosis gene VPS13A in the yeast Saccharomyces cerevisiae|,|
University of British Columbia
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To define the role of caspases and caspase cleavage of htt in the pathogenesis of HD|,|
University of British Columbia
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A molecular basis for replacement tooth formation in reptiles|,|
University of British Columbia (Point Grey Campus)
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MeCP2 and chromatin: An alternative to the global binding hypothesis|,|
University of Victoria
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Role of ABCA1 in brain cholesterol metabolism and brain function|,|
University of British Columbia
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Development of potential therapeutics for influenza via sialidase inactivators|,|
University of British Columbia (Point Grey Campus)
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Structural basis of the glycerol-phosphate and the ribitol-phosphate chain polymerization in teichoic acid biosynthesis in gram-positive bacteria|,|
University of British Columbia (Point Grey Campus)
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Acute lung injury: FasL, apoptosis and protection by erythropoietin|,|
University of British Columbia
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Molecular mechanisms of retrograde transport|,|
University of British Columbia
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Interomics: System-wide proteomic discovery of interactors and substrates of proteases|,|
University of British Columbia (Point Grey Campus)
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Regulation of lymphocyte activation and proliferation and synthesis of pro-inflammatory cytokines by the Caprin-1/G3BP-1 heteromeric complex|,|
University of British Columbia
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SPARC in the repair of the central nervous system|,|
University of British Columbia (Point Grey Campus)
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Mechanical stress: an unexplored factor in regulation of cell signaling in DCIS and early breast cancer progression|,|
University of Victoria
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Characterization of the assembly of type III secretion system of pathogenic Escherichia coli|,|
University of British Columbia
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Clinical

Junior Graduate Studentship

Testing the neural mechanisms of face processing in individuals with Autism: An MEG study|,|
Simon Fraser University
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Using real-time fMRI to modulate metacognitive thought processes in patients with recurrent unipolar depression|,|
University of British Columbia (Point Grey Campus)
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Correlation between results from a new magnetic resonance imaging technique to measure myelin in the spinal cord and somatosensory evoked potentials|,|
University of British Columbia (Point Grey Campus)
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Studies towards the total synthesis of eleutherobin and designed analogues for cancer therapy|,|
Simon Fraser University
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Dimensionality and implications of reduced cognitive performance following kidney transplant|,|
Simon Fraser University
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The effect of intermittent hypoxic and hypercapnic protocols on cerebral blood flow regulation at rest and exercise|,|
University of British Columbia (Point Grey Campus)
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Autism Spectrum Disorders: Identification of novel microdeletion and microduplication syndromes and clinical endophenotypes|,|
University of British Columbia
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Exploring emotional awareness using real-time fMRI|,|
University of British Columbia (Point Grey Campus)
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Nonverbal emotion processing across communication channels|,|
Simon Fraser University
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Dopamine and risky-decision making
University of British Columbia (Point Grey Campus)
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Dynamic suppression of pathological brain oscillations in Parkinson's disease (PD) with virtual environments (VE)|,|
University of British Columbia
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Senior Graduate Studentship

Prosopagnosia and the processing of familiarity, identity and the self|,|
University of British Columbia (Point Grey Campus)
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Independence of identity and expression? A look at facial processing in both healthy and patient populations|,|
University of British Columbia
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Neuropsychological predictors of medication adherence and employment status following kidney transplantation|,|
Simon Fraser University
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The effectiveness of a supplementary inpatient exercise program on upper limb function in individuals with stroke|,|
University of British Columbia
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Quantitative three-dimensional assessment of bone and cartilage in osteoarthritic and normal knees using novel imaging methods and mechanical indentation testing|,|
University of British Columbia
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Female sexual arousal disorder subtypes: Conceptualization, diagnosis and treatment|,|
University of British Columbia (Point Grey Campus)
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The effect of reward expectation and dopamine release on the mechanism of the placebo effect in Parkinson's disease|,|
University of British Columbia
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Links between patellofemoral biomechanics and osteoarthritis|,|
University of British Columbia
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Action Schools! BC: The effect of a school based physical activity model on risk factors for cardiovascular disease in Aboriginal children|,||,|
University of British Columbia
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Acute exercise in individuals with spinal cord injury: friend or foe?|,|
University of British Columbia (Point Grey Campus)
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Early diagnosis of compartment syndrome following tibial fractures using Intra-Compartmental Pressure Monitoring, near infra-red spectroscopy & plasma ischemic markers|,|
University of British Columbia
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Post Doctoral Fellowship

The heart as an immunologic organ: Cardiac myocytes in innate immunity|,|
University of British Columbia
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Topographical disorientation as a predictor of Alzheimer's Disease in patients affected by Mild Cognitive Impairment|,|
University of British Columbia
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Biomechanical energy harvesting|,|
Simon Fraser University
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Effects of prenatal psychotropic medication exposure on critical periods of language development|,|
University of British Columbia
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Health Services

Junior Graduate Studentship

Negotiating international health policy on a local level: HIV positive women and their experiences with infant feeding in Vancouver, Canada|,|
Simon Fraser University
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Measuring equity in access to pharmaceuticals|,|
University of British Columbia (Point Grey Campus)
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Who works in rural areas?: Experiences and characteristics shared by long term health care professionals working in rural areas of Northern British Columbia|,|
University of Northern British Columbia
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Development of clinical standards of care for Huntington disease intermediate allele predictive test results|,|
University of British Columbia
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Senior Graduate Studentship

The structure and process level determinants of improved clinical outcomes in prehospital cardiac arrest and major trauma|,|
University of British Columbia (Point Grey Campus)
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The medical management of human intersex: An evaluation of parent-clinician communication about treatment options|,|
Simon Fraser University
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Estimating current and future direct medical costs associated with HIV/AIDS in British Columbia using an integrated model of clinical disease history and population transmission dynamics|,|
University of British Columbia
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Knowledge translation of health outcome measurement research into clinical practice to improve health care effectiveness and efficiency in a Prevention and Early Active Return-to-work Safely (PEARS) Program|,|
University of British Columbia (Point Grey Campus)
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Adjusting for missing information in multilevel models with a non-binary response: identifying socioeconomic, cultural, demographic and clinical predictors of end-of-life health care service utilization|,|
University of British Columbia
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Characterizing British Columbia's rural and northern home support workforce: A mixed methods investigation of workers and their working lives|,|
University of British Columbia (Point Grey Campus)
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Post Doctoral Fellowship

Pharmacist-initiated intervention trial in osteoarthritis (PHIT-OA)|,|
University of British Columbia
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A preliminary study to assess and develop a Métis community readiness model and indicators of success|,|
University of British Columbia Okanagan
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Population Health

Junior Graduate Studentship

The role of imprinting in placentation and obstetrical complications|,|
University of British Columbia
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Perinatal outcomes in a provincial based cohort of HIV positive mother-infant pairs
University of British Columbia
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Effect of long term air pollution exposure on childhood respiratory diseases in the Georgia Basin: A cohort study|,|
University of British Columbia (Point Grey Campus)
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Remaining patient: Transforming the practices of health care to promote positive outcomes for teen mothers and their children|,|
University of British Columbia (Point Grey Campus)
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An examination of illicit drug use and sexual risk behaviours among a cohort of street-involved youth in Vancouver
University of British Columbia
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Impact of community engaged arts on the health status of older adults|,|
University of British Columbia (Point Grey Campus)
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Evaluating the inclinometer as a novel approach to estimate spinal compression for epidemiological and occupational field studies of back injuries|,|
University of British Columbia (Point Grey Campus)
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Senior Graduate Studentship

Molecular epidemiology of gastric and esophageal cancer survival|,|
University of British Columbia
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What causes Parkinson's Disease? An epidemiologic analysis of occupational exposures|,|
University of British Columbia (Point Grey Campus)
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Safety of home birth: Consequences of hemorrhage in home birth|,|
University of British Columbia
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Person perception in individuals with autism spectrum disorders|,|
University of British Columbia (Point Grey Campus)
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Cognitive, emotional, and behavioural implications of vicarious trauma|,|
University of British Columbia (Point Grey Campus)
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Spiritual coping in Portuguese immigrants to British Columbia|,|
University of British Columbia (Point Grey Campus)
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Coping within families with children with ADHD
University of British Columbia (Point Grey Campus)
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Exposure to residential air pollution and diagnosis of acute otitis media during the first two years of life in British Columbia, Canada|,|
University of British Columbia (Point Grey Campus)
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Goal adjustment processes and caregiver health: Can giving up be a good thing?|,|
University of British Columbia (Point Grey Campus)
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Wheelchair use by nursing home residents: An exploration of the relationship between wheelchair use, activity participation and quality of life|,|
University of British Columbia
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How the eating disorder therapist's personal experience of an eating disorder influences the therapeutic relationship with clients who have eating disorders: A grounded theory|,|
University of British Columbia (Point Grey Campus)
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Improving public health through active transportation: Understanding the influence of urban infrastructure on decisions to travel by bicycle|,|
University of British Columbia (Point Grey Campus)
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Post Doctoral Fellowship

Measurement error issues in studying the effect of gene-environment interactions on disease risks|,|
University of British Columbia
Jointly funded with Canadian Cancer Society - BC & Yukon Division
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Development and evaluation of a novel group educational intervention to promote partner support for people with rheumatoid arthritis|,|
Simon Fraser University
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Molecular pathways linking socioeconomic status, stress experiences, and asthma severity in children|,|
University of British Columbia (Point Grey Campus)
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