Dr. Aaron Phillips’ research interests involve cerebrovascular regulation and its relationship to clinical outcomes. Dysfunctional cerebral blood flow regulation is implicated in orthostatic intolerance, cognitive dysfunction, mood disorders, fatigue, as well as increased risk of stroke.
Through the use of cutting-edge heart and brain imaging techniques, Dr. Phillips is evaluating the role cerebrovascular function plays in the development of clinical outcomes within a variety of populations and circumstances, including those with spinal cord injury as well as those diagnosed with schizophrenia.
Most recently, Dr. Phillips has studied cerebral blood flow during severe swings in blood pressure (i.e. systolic blood pressure from 60-250 mmHg) in those with spinal cord injury, as well as completed a clinical trial evaluating the effectiveness of a pharmaceutical therapy for improving cerebrovascular function. Moving forward, Dr. Phillips will evaluate cerebrovascular function during invasive surgeries and other medical procedures.
University: University of British Columbia
Phillips AA, Ainslie P, Krassioukov AV, Warburton DE. Regulation of Cerebral Blood Flow after Spinal Cord Injury. J Neurotrauma. 2013 Jun 13. (PubMed abstract)
Phillips AA, O’Leary DD. Letter by Phillips and O’Leary regarding article, “systemic and pulmonary vascular dysfunction in children conceived by assisted reproductive technologies”. Circulation. 2013 Mar 5;127(9):e476. doi: 10.1161/CIRCULATIONAHA.112.111567. (PubMed abstract)
Phillips AA, Bredin SS, Cote AT, Drury CT, Warburton DE. Aortic distensibility is reduced during intense lower body negative pressure and is related to low frequency power of systolic blood pressure. Eur J Appl Physiol. 2013 Mar;113(3):785-92. doi: 10.1007/s00421-012-2489-3. Epub 2012 Sep 14. (PubMed abstract)
Phillips AA, Cote AT, Bredin SS, Krassioukov AV, Warburton DE. Aortic stiffness increased in spinal cord injury when matched for physical activity. Med Sci Sports Exerc. 2012 Nov;44(11):2065-70. doi: 10.1249/MSS.0b013e3182632585. (PubMed abstract)
Phillips AA, Krassioukov AV, Ainslie PN, Warburton DE. Baroreflex function after spinal cord injury. J Neurotrauma. 2012 Oct 10;29(15):2431-45. doi: 10.1089/neu.2012.2507. Epub 2012 Sep 20. (PubMed abstract)