Jack Chen

Dr. Jack Chen is an associate professor in the Department of Molecular Biology and Biochemistry in the Faculty of Science at Simon Fraser University. He is a Canadian Institutes of Health Research New Investigator and a Michael Smith Foundation for Health Research Scholar. Research in his laboratory is also funded by Natural Science and Engineering Research Council discovery grants.

Chen’s current research interests include algorithm development for comparative genomics, comparative analysis of malaria parasites, liver cancer genomics, transcriptional regulation of ciliary genes, and ciliopathies.

Affiliation

University: Simon Fraser University
Faculty: Science
Department: Molecular Biology and Biochemistry
Position: Associate Professor

Recent Publications

Tarailo-Graovac M, Chen N. Proper cyclin B3 dosage is important for precision of metaphase-to-anaphase onset timing in Caenorhabditis elegans. G3 (Bethesda). 2012 Aug;2(8):865-71. doi: 10.1534/g3.112.002782. Epub 2012 Aug 1. (PubMed abstract)

Uyar B, Chu JS, Vergara IA, Chua SY, Jones MR, Wong T, Baillie DL, Chen N. RNA-seq analysis of the C. briggsae transcriptome. Genome Res. 2012 Aug;22(8):1567-80. doi: 10.1101/gr.134601.111. Epub 2012 Jul 6. (PubMed abstract)

Frech C, Chen N. Genome comparison of human and non-human malaria parasites reveals species subset-specific genes potentially linked to human disease. PLoS Comput Biol. 2011 Dec;7(12):e1002320. doi: 10.1371/journal.pcbi.1002320. Epub 2011 Dec 22. (PubMed abstract)

Chu JS, Tarailo-Graovac M, Zhang D, Wang J, Uyar B, Tu D, Trinh J, Baillie DL, Chen N. Fine tuning of RFX/DAF-19-regulated target gene expression through binding to multiple sites in Caenorhabditis elegans. Nucleic Acids Res. 2012 Jan;40(1):53-64. doi: 10.1093/nar/gkr690. Epub 2011 Sep 8. (PubMed abstract)

She R, Chu JS, Uyar B, Wang J, Wang K, Chen N. genBlastG: using BLAST searches to build homologous gene models. Bioinformatics. 2011 Aug 1;27(15):2141-3. doi: 10.1093/bioinformatics/btr342. Epub 2011 Jun 8. (PubMed abstract)