Dr. Marinko Sarunic’s research is devoted to developing non-invasive optical imaging systems to investigate diseases that cause blindness, with a particular emphasis on glaucoma and retinal degeneration. One of his main focuses is optical coherence tomography (OCT), a non-invasive, three-dimensional, micrometer-resolution imaging technique using interference of near-infrared light.
Sarunic’s laboratory designs and constructs high resolution OCT and fluorescence imaging systems for studies in ophthalmology and vision science.
Jian Y, Zawadzki RJ, Sarunic MV. Adaptive optics optical coherence tomography for in vivo mouse retinal imaging. J Biomed Opt. 2013 May 1;18(5):56007. doi: 10.1117/1.JBO.18.5.056007. (PubMed abstract)
Lee S, Fallah N, Forooghian F, Ko A, Pakzad-Vaezi K, Merkur AB, Kirker AW, Albiani DA, Young M, Sarunic MV, Beg MF. Comparative analysis of repeatability of manual and automated choroidal thickness measurements in nonneovascular age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013 Apr 23;54(4):2864-71. doi: 10.1167/iovs.12-11521. (PubMed abstract)
Jian Y, Wong K, Sarunic MV. Graphics processing unit accelerated optical coherence tomography processing at megahertz axial scan rate and high resolution video rate volumetric rendering. J Biomed Opt. 2013 Feb;18(2):26002. doi: 10.1117/1.JBO.18.2.026002. (PubMed abstract)
Young M, Lebed E, Jian Y, Mackenzie PJ, Beg MF, Sarunic MV. Real-time high-speed volumetric imaging using compressive sampling optical coherence tomography. Biomed Opt Express. 2011 Sep 1;2(9):2690-7. doi: 10.1364/BOE.2.002690. Epub 2011 Aug 24. (PubMed abstract)
Sarunic MV, Yazdanpanah A, Gibson E, Xu J, Bai Y, Lee S, Saragovi HU, Beg MF. Longitudinal study of retinal degeneration in a rat using spectral domain optical coherence tomography. Opt Express. 2010 Oct 25;18(22):23435-41. doi: 10.1364/OE.18.023435. (PubMed abstract)
Xu J, Molday LL, Molday RS, Sarunic MV. In vivo imaging of the mouse model of X-linked juvenile retinoschisis with fourier domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2989-93. doi: 10.1167/iovs.08-2542. Epub 2009 Jan 31. (PubMed abstract)