Dr. Stuart Turvey, MBBS, DPhil, FRCPC has been appointed as the Canada Research Chair in Pediatric Precision Health. He is a Professor of Pediatrics at The University of British Columbia where he holds the Aubrey J. Tingle Professorship in Pediatric Immunology. He is a clinician-scientist and Pediatric Immunologist based at BC Children’s Hospital.
Dr. Turvey’s research program is focused on determining the early-life origins of asthma and allergic disease, as well as harnessing the power of genomics to diagnose, treat and prevent pediatric immune disorders. His ability to transition from the clinic to the lab allows Dr. Turvey to take a precision health approach that is sensitive to the developmental course of the child. His work determines and responds to the underlying cellular, molecular and genetic abnormalities responsible for disease.
Dr. Turvey and his team generate new knowledge to define the mechanisms of disease pathogenesis and, ultimately, to identify new strategies to treat and even prevent these burdensome and often life threatening conditions.
For an up-to-date list of publications by Dr. Turvey, please see BCCHR.
Ali S, Hirschfeld AF, Mayer ML, Fortuno ES, Corbett N, Schneiderman J, Fjell CD, Hsu K, Marr N, Yan J, Akhabir L, Aminuddin F, Lacaze-Masmonteil T, Hegele RG, Becker A, Chan-Yeung M, Hancock REW, Kollmann TR, Daley D, Sandford AJ, Lavoie PM, Turvey SE (2013). Functional genetic variation in NFKBIA and susceptibility to childhood asthma, bronchiolitis and bronchopulmonary dysplasia. J Immunol (in press).
Blohmke CJ, Mayer ML, Fjell CD, Sze M, Tang A, Hirschfeld AF, Chilvers MA, Hogg JC, Falsafi R, Hancock REW, Turvey SE (2012). ER stress, the unfolded protein response and inflammation in lung disease of humans with cystic fibrosis. J Immunol 189(11):5467-75.
Turvey SE, Leo SH, Boos A, Deans GD, Prendiville J, Crawford RI, Senger C, Conley ME, Tilley P, Junker A, Janz L, Azana R, Hoang L, Morton TL (2012). Successful approach to treatment of Helicobacter bilis infection in X-linked agammaglobulinemia. J Clin Immunol 32(6):1404-8.
N. Marr, Turvey SE (2012). Role of human Toll-like receptor 4 in respiratory syncytial virus-induced nuclear factor-κB activation, viral entry and replication. Innate Immunity 18(6):856-65.
Blohmke CJ, Park J, Hirschfeld AF, Victor RE, Schneiderman J, Stefanowicz D, Chilvers MA, Durie PR, Corey M, Zielenski J, Dorfman R, Sandford AJ, Daley D, Turvey SE (2010). Toll-like receptor 5 is an anti-inflammatory target and modifier gene in cystic fibrosis. J Immunol 185(12):7731-8.