The Centre for Heart Lung Innovation (HLI) was established as the Pulmonary Research Laboratory in 1977 by Drs. James Hogg and Peter Pare. Since then, it has grown dramatically in scope, size and worldwide impact.

Basic and clinician scientists work together in an exciting multidisciplinary environment to address vital issues in heart, lung and critical care disease. Situated within Providence Health Care’s St. Paul’s Hospital, a University of British Columbia teaching hospital, the HLI is a translational research centre using basic molecular and cellular research discoveries to develop innovative approaches to prevent and treat human disease through complementary and connected clinical research.

The HLI focuses on developing solutions to diseases that are major causes of morbidity, mortality, and societal costs in Canada and worldwide. These include atherosclerosis and heart failure, emphysema and other chronic pulmonary diseases, severe infections, and multiple organ failure. The centre seeks out the underlying causes in order to develop strategies for prevention and treatment. Basic discoveries are linked to improved health care through clinical research and teaching, and by translating new knowledge into clinical practice at St. Paul’s Hospital and around the world. 

HLI is one of several renowned research centres based at Providence Research.

Funding interests

Award type

Research Trainee, Scholar


Research interests

  • pulmonary (respiratory, ventilation)
  • cardiovascular (heart, vascular)
  • ICU with a focus on sepsis (specifically bacterial clearance and/or the host response)

Research location/affiliation: Providence Health Care/Providence Research/Centre for Heart Lung Innovation

 

Awards

2022

Recipient

Yasir Mohamud

Award type

Research Trainee award


Project title

Innate immune mechanisms of viral myocarditis: Role of the cytosolic DNA-sensing pathway

Recipient

Stephanie Sellers

Award type

Scholar award


Project title

Valvular heart disease and bioprosthetic heart valves: Defining mechanisms of degeneration and therapeutic discovery from bedside to bench

2021


Award type

Research Trainee award


Project title

Understanding the link between lung genomics, transcriptomics, and sex differences in COPD

2020

Recipient

Rachel Eddy

Award type

Research Trainee award


Project title

Ventilation Heterogeneity in Asthma, COPD and Asthma-COPD Overlap: Oscillometry and Pulmonary MRI

2019

Recipient

Michele Schaeffer

Award type

Research Trainee award


Project title

The effects of 60% oxygen during exercise training in patients with fibrotic interstitial lung disease

2018


Award type

Research Trainee award


Project title

Investigating the role of skeletal muscle dysfunction on dyspnea and exercise intolerance in interstitial lung disease

Recipient

Stephanie Sellers

Award type

Research Trainee award


Project title

Structural valve degeneration in bioprosthetic heart valves