Population Health

Towards TB elimination in Canada: Optimizing tuberculosis screening and prevention

The World Health Organization (WHO) aims to eliminate TB by 2050, but Canada is not on target to meet that goal. To reach our national TB elimination targets, we must reduce TB rates by 10% per year but we are only reducing TB rates by 2% per year. My research program is aimed at developing evidence to improve TB screening, prevention and treatment policies in order to accelerate TB elimination in British Columbia (BC) and Canada.  

Primary Investigator: 
Year: 
2019

Making Healthy Connections: A Critical Anti-Racist and Decolonizing Geography of Immigrant and Indigenous Relations in Northern British Columbia

While resources support immigrant well-being in urban settings in southern Canada, little research exists on recent immigrants in northern communities. Moreover, while new research is emerging about the health disparities of Indigenous communities in remote and rural settings, there is very little research that brings the question of immigrant and Indigenous relations together.

Primary Investigator: 
Award Type: 
Year: 
2019

Disease-modifying Drug Safety and Effectiveness in Multiple Sclerosis [DRUMS]

British Columbia (BC) and Canada have some of the world's highest rates of multiple sclerosis (MS). The goal of this research is to find out how safe and effective the drugs used to treat MS are when used in the everyday, real world in BC and Canada.

Primary Investigator: 
Award Type: 
Year: 
2019

A Lifespan Approach Towards Understanding the Importance of Movement Skills for Health-Enhancing Physical Activity Participation

Participation in regular physical activity is associated with reduced risks of cardiovascular disease, overweight/obesity, type 2 diabetes mellitus, numerous cancers, mental and reproductive health problems, and osteoporosis. Yet, only 9% of Canadian children and adolescents and 20% of Canadian adults meet physical activity guidelines. An essential component of being active involves having the skills needed to successfully participate in an activity.

Primary Investigator: 
Award Type: 
Year: 
2019

Investigating the impact of evolving cannabis access and use on high-risk drug use behaviours and addiction treatment

Cannabis remains the most widely produced, trafficked and consumed illicit drug worldwide, and at this time Canada and many other countries are implementing alternative regulatory approaches to cannabis. While research on cannabis has traditionally focused on the harms of cannabis use, an emerging body of evidence suggests that cannabis use can also alter high-risk drug practices, such as reducing cocaine use, opioid use and associated overdose.

Primary Investigator: 
Award Type: 
Year: 
2019

Prevalence, patterns, and harms associated with the co-injection of illicit opioids and crystal methamphetamine

Crystal methamphetamine use is associated with a wide array of physical and social harms. In spite of this, its prevalence is rising in many parts of North America. Several small studies have suggested increasing rates of co-injection of methamphetamine and opioids, though no research has focused on the specific harms associated with this trend. In Vancouver, preliminary reports have noted a similar pattern, in a context where fentanyl has become the most widely used form of illicit opioid.

Primary Investigator: 
Award Type: 
Year: 
2019

Developing long-, short-, and near-term dynamic models of risk and resilience for intentional self-harm in BC youth

My research aims to answer two questions: when and under what circumstances do some young people intentionally physically harm themselves, and how can we improve our clinical tools to reduce these behaviours? Intentional self-harm is alarmingly prevalent in young British Columbians: around 5-7% of BC youth have attempted to end their own lives, 10-15% have experienced serious suicidal thoughts, and 15-18% have engaged in non-suicidal self-injury. These behaviours can have devastating impacts on youth, their families, and their communities.

Primary Investigator: 
Award Type: 
Year: 
2019

Adapting BC’s healthcare system for equitable and tailored service provision to sexual and gender minorities

Lesbian, gay, bisexual, transgender, and queer (LGBTQ) people face judgment and discrimination on the basis of their sexualities and genders. This leads many LGBTQ people to avoid seeking treatment from the healthcare system, to hide aspects of their sexuality/gender when seeking care, or to selectively visit LGBTQ-affirming providers.

The goal of this research program is to develop a comprehensive understanding of healthcare access patterns among LGBTQ people in BC.

Objectives:

Primary Investigator: 
Award Type: 
Year: 
2019

Advancing nutritional hematology to reduce the burden of anemia and inform nutrition policy

Anemia is a condition in which there is a decrease or destruction of red blood cells causing inadequate transport of oxygen throughout the body. It is a major public health problem affecting ~25% of the global population, or ~9 million Canadians of all ages.

Primary Investigator: 
Award Type: 
Year: 
2019

Promoting Mental Health and Addressing Substance Use in Canadian Youth through Collaborative Research and Intervention

Mental health and substance use (MHSU) challenges are leading health issues facing youth globally. In Canada, 20% of the youth population experiences mental health disorders, and youth aged 15-24 have the highest rates of past year substance use and related harms. To address these concerns, MHSU researchers and advocates argue for a population health approach incorporating promotion, prevention, and treatment within a 'healthy public policy' framework.

Primary Investigator: 
Award Type: 
Year: 
2019

Improving substance use care for gay, lesbian and bisexual youth in British Columbia

Gay, lesbian, and bisexual youth (GLBY) are at increased risk of experiencing substance use disorders (SUD) in comparison to their heterosexual counterparts. The aim of Dr. Ferlatte’s research is to identify the factors associated with SUD experienced by GLBY to inform interventions.

This will include:

Primary Investigator: 
Award Type: 
Year: 
2018

Population-level impact of hepatitis C virus (HCV) direct-acting antiviral therapies on extrahepatic manifestations

Hepatitis C virus is an important public health concern in Canada; however, there is limited information concerning the impact of new direct-acting antiviral therapies on manifestations outside the liver (extrahepatic manifestations, or EHMs), including chronic diseases, cancers, and health-care resource utilization in Canada.

This knowledge is important, as new HCV treatments are generally restricted to those with advanced liver disease and there are no estimates of the reductions in EHMs that can be achieved with expansion of therapy.

Primary Investigator: 
Award Type: 
Year: 
2018

3, 2, 1... Might one dose of HPV vaccine be enough to prevent HPV-associated cancer?

Human papillomavirus (HPV) infection is a prerequisite for the development of cervical cancer. Screening for cervical cancer after HPV infection is possible by cervical smear testing, and since 2006 direct prevention of HPV infection has been available in the form of three different vaccines.

Primary Investigator: 
Award Type: 
Year: 
2018

Optimizing PrEP and TasP adherence among substance using gay, bisexual, and other men who have sex with men

While increased access to HIV treatment and other health services has contributed to significant declines in HIV among several key populations in British Columbia (BC), it is estimated that as many as 1 in 6 gay, bisexual, and other men who have sex with men (gbMSM) will be diagnosed with HIV in their lifetime.

Primary Investigator: 
Award Type: 
Year: 
2018

Studying the role of modifiable risk factors: Nutrition and body weight for the prevention of cancer

Nearly half of Canadians will be diagnosed with cancer during their life. Healthy eating, a healthy body weight, and regular physical activity can prevent one-third of cancers. Yet, many Canadians do not engage in these lifestyle behaviours. New approaches to improve diet-cancer research are needed to move the field forward and reduce the burden of cancer on Canadians.

Primary Investigator: 
Award Type: 
Year: 
2018

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