Team Start-Up Award

Public Health Services Renewal in BC

Canada’s public health system faces serious systemic challenges for adequately meeting the health needs of the population. To help guide a plan for improvement and renewal of public health services in BC, the BC Ministry of Health has developed a Framework for Core Functions in Public Health. This framework defines the core activities of a comprehensive public health system, and serves as the roadmap by which the province is planning and investing in public health services.

Primary Investigator: 
Award Type: 
Year: 
2008

Optimization of Trauma systems

Every year approximately 400,000 British Columbians suffer a traumatic injury — the leading cause of mortality and morbidity in Canada. The development of trauma systems to improve the access of injured patients to timely, and often life saving care is a health care priority. Unfortunately, access to timely and appropriate trauma care is not universal in BC. For example, injured patients in rural communities typically face economic, social and geographical barriers to care.

Primary Investigator: 
Award Type: 
Year: 
2008

Health Innovation Design and Evaluation Research Team

In their ongoing efforts to improve health outcomes, decrease health care costs, and increase administrative efficiency, health care agencies are increasingly investing in information-based technologies (IT). Recently, the Canadian government highlighted the need for developing new methods for evaluating new health sector technologies in order to provide insight into the challenges associated with increased use of IT in health care settings.

Primary Investigator: 
Award Type: 
Year: 
2008

Rehabilitation Aimed at Muscle Performance

Research indicates that sustained physical inactivity leads to chronic degenerative conditions and premature death. Currently, approximately 75% of Canadians aged 50-75 years and 84% of those over 75 are physically inactive. The associated health and economic burdens will continue to escalate as the proportion of elderly British Columbians increases to 20% of the population by 2026.

Primary Investigator: 
Award Type: 
Year: 
2008

Team for Monitoring and Control of Abnormal Brain Dynamics

The majority of treatments for neurological diseases involve drugs. Yet maintaining a steady state of medications in a person’s system may not be effective in targeting abnormal brain activity that is transient and oscillating. Therefore, patients may have to continually take drugs for conditions that only manifest themselves intermittently – such as with seizures – or to take drugs that disrupt normal brain activity.

Primary Investigator: 
Award Type: 
Year: 
2007

Spinal Cord Injury Proteomics

Each year, approximately 1,500 Canadians sustain an acute traumatic spinal cord injury (SCI). Disability from an SCI results both from the initial trauma, and secondary cell damage that occurs due to pathophysiological processes after the initial SCI event. Current research suggests that neuroprotective drugs need to be administered early after injury to head off secondary cell damage, yet current diagnostics aren’t able to determine and classify the exact severity of the spinal injury within this timeframe.

Primary Investigator: 
Award Type: 
Year: 
2007

Detecting, Treating and Preventing Drug-Related Morbidity

In Canada, 7.5 per cent of hospital admissions are complicated by an adverse event related to medical care that leads to death, disability, or a prolonged hospital stay. Adverse drug related events (ADREs) represent the most common cause of preventable non-surgical adverse events, with up to 130,000 patients in British Columbia (BC) presenting to Emergency Departments with a symptomatic ADRE. However, there are currently no efficient screening strategies for ADREs. This team is working to develop and evaluate a clinically effective, resource-efficient screening strategy.

Primary Investigator: 
Award Type: 
Year: 
2007

TB Research Group

Mycobacterium tuberculosis – the bacteria that causes tuberculosis (TB) – is the most devastating infectious agent of mortality worldwide: it is carried by one third of all humans and kills nearly two million people annually. In BC and throughout Canada, First Nations and Inuit communities are at an especially high risk, and more than 300 new or relapsed TB cases are reported each year.

Primary Investigator: 
Award Type: 
Year: 
2007

Risk Reduction in Mental Health

Individuals with a major mental disorder are at heightened risk of committing acts of violence, being victimized by others, and harming themselves. These adverse outcomes – and the factors that contribute or mitigate them – are known to be interconnected. However, there hasn’t been a coordinated research platform that addresses all three outcomes together and identifies how different risk and protective factors affect each of these outcomes individually, and in combination, over time.

Primary Investigator: 
Award Type: 
Year: 
2006
Health Category: 

COPD And Inflammation Team (CAIT)

In BC, more than 74,000 adults have chronic obstructive pulmonary disease (COPD) and 10,000 patients require hospitalization each year for related illnesses, such as chronic bronchitis and emphysema. Lung inflammation is the defining symptom of COPD, and may also be responsible for its progression and complications, including lung cancer and vascular disease. Currently, there are few effective therapies available to treat COPD.

Primary Investigator: 
Award Type: 
Year: 
2006
Health Category: 
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