Centre for Heart Lung Innovation

The Centre for Heart Lung Innovation (HLI) was established as the Pulmonary Research Laboratory in 1977 by Drs. James Hogg and Peter Pare. Since then, it has grown dramatically in scope, size, and worldwide impact.

Basic and clinician scientists work together in an exciting multidisciplinary environment to address vital issues in heart, lung, and critical care disease. Situated within Providence Health Care’s St. Paul’s Hospital, a University of British Columbia teaching hospital, the HLI is a translational research centre using basic molecular and cellular research discoveries to develop innovative approaches to prevent and treat human disease through complementary and connected clinical research.

The HLI focuses on developing solutions to diseases that are major causes of morbidity, mortality, and societal costs in Canada and worldwide. These include: atherosclerosis and heart failure, emphysema and other chronic pulmonary diseases, severe infections and multiple organ failure. The centre seeks out the underlying causes in order to develop strategies for prevention and treatment. Basic discoveries are linked to improved health care through clinical research, teaching, and by translating new knowledge into clinical practice at St. Paul’s Hospital and around the world. 

HLI is one of three renowned research centres based at Providence Health Care Research Institute.


Current co-funding interests

Award types Areas of interest
Pulmonary (respiratory, ventilation)


Cardiovascular (heart, vascular), pulmonary (respiratory, ventilation), ICU with a focus on sepsis (specifically bacterial clearance and/or the host response)

Research location / affiliation: Providence Health Care/Providence Health Care Research Institute/Centre for Heart Lung Innovation/UBC James Hogg Research Centre