Developing a safe and effective analgesic for chronic pain relief

Principal Investigator: 
University: 
University of British Columbia
Faculty: 
Faculty of Pharmaceutical Sciences

About 6 million Canadians report a form of chronic pain, yet half of the sufferers do not get enough pain relief from their medications. This severely affects their quality of life and has significant social and economic burdens. Opioid medications, such as morphine, are the most powerful pain killers available, but these drugs also cause serious side effects, such as suppressed breathing, leading to a high risk of death from overdose.

In 2016, there were 2,861 opioid overdose deaths in Canada, and British Columbia (BC) reported the highest opioid-related death rate, which was three times the national average. The overdose rate in BC increased 17-fold from 2011 to 2016. This worsening opioid epidemic resulted in changes in opioid prescribing standards, and half of the chronic pain sufferers can no longer access opioid drugs in BC. Dr. Li will lead a team to develop a new, effective, and safe drug for chronic pain relief. This new drug will improve pain relief options and access for patients who suffer from chronic pain.

The team will work with companies to ensure this new drug is readily available to pain sufferers through primary care to all populations in BC and the whole of Canada.

Host Institution: 
University of British Columbia
Research Location: 
University of British Columbia - Vancouver
Year: 
2019