ophthalmology

Studying motion processing with eye movements in healthy older adults and patients with ophthalmic diseases

As our population ages, an increasing number of Canadians experience difficulties with their vision. Although it is well known that both normal aging and age-related eye disease can affect a person's ability to see fine detail (such as in reading), tests of visual acuity used in regular eye examinations do not provide a complete picture of a person's ability to see in everyday situations, such as exercising and driving, where moving objects are often involved.

Primary Investigator: 
Award Type: 
Year: 
2019

Cellular resolution OCT for clinical ophthalmology

Two of the leading causes of irreversible vision loss in developed countries are age-related macular degeneration (AMD) and diabetic retinopathy (DR). These diseases lead to the death of photoreceptors, the light-sensitive cells in the retina located at the back of the eye.

Treatments are currently available for “wet” AMD and DR, but there are currently no effective treatments for “dry” AMD. The key to preserving sight is early diagnosis, and monitoring the effects of the novel therapies in development.

Primary Investigator: 
Year: 
2018

In vivo multi-resolution functional optical imaging for investigation of age-related macular degeneration (AMD) process

Vision loss from age-related macular degeneration (AMD) and other retinal degeneration diseases is due to the loss of the light sensitive photoreceptor cells in the eye. This is often secondary to dysfunction of the retinal pigment epithelium (RPE). 

The photoreceptor and RPE cells are arranged in a characteristic mosaic. The mosaic is an accurate clue to how healthy these layers are. However, attempts to visualize these mosaics have been so far unsuccessful, despite technological advancements in conventional ophthalmic imaging. 

Primary Investigator: 
Award Type: 
Year: 
2017
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